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Earlier amylin analogs like pramlintide were short-acting and needed dosing with every meal, which made them a hassle and limited their reach

In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks

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For qPCR, a single piece of lens capsule constituted one sample