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In vitro models of the blood-cerebrospinal fluid barrier and their use in neurotoxicological research

[PubMed] [Google Scholar] 69.Gregory JF

Varoglutamstat ( 17 , formerly PQ912), the first small molecule glutaminyl cyclase inhibitor to enter phase II clinical trials, targets an enzyme that catalyzes the conversion of glutamate to pyroglutamate at the N-terminus of A

Gold KA, Lee JJ, Ping Y, Behrens C, Liu D, Lee HY, Koo JS, Lotan R Solis L, Rinsurongkawong W, Stewart DJ, Hofstetter WL, Swisher SG , Lippman SM, Wistuba II, Hong WK, Kim ES