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While oral bioavailability is lower than subcutaneous administration, these studies established that even high oral doses maintained excellent safety profiles, though higher doses (54 mg) were associated with increased gastrointestinal discomfort

The recommended daily dosage is 100-400 mg, available in tablets, capsules, or powder form

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3-D cell discs were formed by culturing vascular smooth muscle cells in collagen first and then 3-D discs with similar size were incubated in different media for 24 h