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The CD38 hydrolase activity is largely responsible for the conversion of NAD + to ADO within the hypoxic, acidic MM niche [25]

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The search strategy was initially developed for PubMed using keywords and MeSH terms and was then adapted to the other databases

These bispecific constructs, characterized by their small size, high solubility and extended half-life facilitated by the integration of an albumin-specific sdAb, have demonstrated potent cytotoxicity against tumor cells, exceeding the ADCC of Daratumumab [94]