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Description

The stabilization and nuclear translocation of Nrf2 result in the transcription of antioxidant response element-regulated genes such as HO-1, NQO1, GCLC, SOD, catalase, and GPx, which together enhance glutathione synthesis, maintain mitochondrial redox balance, suppress lipid peroxidation, and improve cellular resilience to oxidative insults

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Granneman JG, Moore HP, Krishnamoorthy R, Rathod M

Two are constitutive (synthesized at a constant rate), Ca 2+ calmodulin-dependent enzymes

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Below, the beneficial or inhibitory impact of these diet-derived and physiological luminal factors on intestinal zinc bioavailability as well as physiological basolateral factors will be briefly summarized (Figure 4)