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The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway

Weeks 5-6: Continued progress, though rate of improvement may slow as receptors begin to desensitize

W., Shu, L

Briefly, an allelic exchange substrate (AES) harboring 1 kb sequences of upstream and downstream homology to the target gene locus, flanking Hygromycin resistance gene cassette, was constructed in the suicidal vector pJM1