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78 A compelling example bridging developmental and disease perspectives is the patent ductus arteriosus (PDA), which illustrates heartlung cross-talk across life stages

Mitochondria-nucleus interactions: epigenetic regulation and metabolic feedback In ovarian cells, mitochondria-nucleus interactions are crucial for maintaining cellular energy balance, genome stability, and supporting key processes including follicle development, ovulation, and corpus luteum formation

Ivanov I, Saam J, Kuhn H, Holzhtter H-G (2005) Dual role of oxygen during lipoxygenase reactions

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125 Notably, ELISA demonstrate that IDH1 level is also significantly elevated in the plasma of NSCLC patients, suggesting that it can be used as a potential plasma biomarker