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ACPAs promote IL-1 production in rheumatoid arthritis by activating the NLRP3 inflammasome

Sun T-C, et al

Eur Rev Aging Phys Act 17: 2, 2020

In one clinical study, healthy fasted individuals who received acetate and propionate did not show increases in serum free fatty acids, presumably due to hepatic glucose production rather than DNL to compensate for fasting-induced hypoglycemia 143