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Specifically, null variants of the GSTM1 and GSTT1 alleles contain large deletions, and individuals who inherit two copies of the GSTM1 -null or GSTT1 -null alleles cannot produce the corresponding GST enzymes (54)

9.4 Role of NAC in viral infections including COVID 19 N-acetylcysteine inhibits replication of influenza A and other respiratory viruses in cell cultures and suppresses inflammatory mediators (CXCL8, CXCL10, CCL5, H 2 O 2 , IL-6) by blocking NF-B and p38 MAPK activation (127, 128)

Murugan, S., Solanki, H., Purusothaman, D., Bethapudi, B., Ravalji, M., Mundkinajeddu, D.: Safety evaluation of standardized extract of curcuma longa (NR-INF-02): a 90-day subchronic oral toxicity study in rats