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Patel et al., 2014), suggesting that glucose oxidation, and not astrocyte-derived lactate, plays a major role in neuronal energy production in physiological conditions

Its molecular mechanism involves the vagus nerve activating the 7nAChR of alveolar macrophages and epithelial cells, triggering the JAK2/STAT3 and PI3K/Akt signaling pathways, inhibiting the activation of NF-B and the NLRP3 inflammasome, thereby reducing the release of pro-inflammatory factors and neutrophil infiltration, protecting the alveolar-capillary barrier, and alleviating lung injury (181)

W.LotteauV.SetteA.FinkP.et al (1990)

Concerns were also raised about a potential link of glutathione use to long-term skin cancer risk

Anekwe, MD, MPH Contributor