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Conversely, other studies report reductions in fasting glucose, mean daily glucose, and insulin requirements (130), along with attenuated inflammatory responses during the honeymoon period (the early post-diagnosis phase characterized by residual -cell function and lower insulin requirements) through decreased serum TNF- levels, thereby prolonging honeymoon duration (131)

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Moreover, replacements of Lys105 resulted in a reciprocal increase of the K m app (GSSCys) values and decrease of the K m app (GSH) values (Fig

This paper systematically reviews the molecular mechanisms of disulfidptosis, elucidates its regulatory role in male cancer cellsincluding key regulatory genes and therapeutic target potentialand discusses its application value and challenges as a potential therapeutic target based on clinical research

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