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The presence of 0.1 mM IPTG in the culture, however, nearly halved the growth rate to 0.036 0.004 h 1 (Fig

In studies, researchers linked low levels of vitamin D to symptom flares, fatigue, poor mental function, kidney disease, osteoporosis and a greater risk of heart disease and high blood pressure (x, x, x, x, x)

However, the latter group is not charged, which may explain the lower potency of CYC116

Another metabolic pathway altered by fumarate accumulation is the PNC, where the increase of fumarate causes the reversal of adenylosuccinate lyase to form adenylosuccinate, altering de novo purine biosynthesis [19] and making cells reliant on the salvage pathway to support purine synthesis

MdB, SH, JV, and JC wrote sections of the manuscript