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Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of ataxia-telangiectasia brain organoids

Catalpol also promotes the uncoupling of Galectin-3 and CD146 molecular complexes induced by AGEs, improving endothelial damage in hepatic sinusoids and reducing the release of monocyte chemoattractant protein-1 (MCP-1) and intercellular adhesion molecule-1 (ICAM-1)