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Mauras N, Haymond MW (2005) Are the metabolic effects of GH and IGF-I separable

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Key: = upregulated, = downregulated, DNMT = DNA methyltransferase

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36 Current evidence suggests a possible link to depressive or suicidal ideation specific to semaglutide 37, and a clearly higher incidence of gastrointestinal adverse events compared with liraglutide.38 Both remain FDA-approved and well-studied

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