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This is evidenced by the negligible affinity of amylin or pramlintide for the isolated CTR ECD 19,20 , and by loss of affinity and/or potency of P32Y substituted CT peptides at the CTR 18,20

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Water Solubility: Because it is highly water-soluble, it is best introduced in the aqueous phase of your formulation at a temperature below 40C to preserve its bioactivity

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doi: 10.1007/s00394-015-1104-x