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TMAO prolongs the hypertensive effect of angiotensin II (Ang II) and increases water reabsorption and has emerged as a potential biomarker of hypertension ( Figure 5 )

If not treated, breathing problems, seizures, coma, and sometimes even death can occur.Metabolic crises happen more often in people with certain metabolic disorders (some fatty acid oxidation disorders, amino acid disorders, and organic acid disorders)

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Bloating, characterized by abdominal discomfort and distension, is also common and may be related to dietary factors or impaired digestion[23]