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The Mounjaro FDA prescribing information does not list local injection-site reactions on their own as a reason to discontinue

2013 Apr;31(1):31-5

Hepatocellular carcinoma: signaling pathways and therapeutic advances

The international journal of biochemistry & cell biology, 29(5), 743-751

Monitoring should be specific Depending on the goal, monitoring may include: Body composition trends, not just scale weight Blood pressure and resting heart rate Fasting glucose, insulin, A1c Lipids and inflammatory markers Liver enzymes, kidney function Thyroid markers when relevant Nutrient status, especially if appetite drops Sleep data, subjective and objective if available You also need a plan for what happens if you stop