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While astrocytes primarily synthesize Gln, neurons uptake Gln, which is then reconverted into Glu by glutaminase [4]

Knocking down Nrf2 in RA fibroblast-like synovial cells (FLSs) hinders the Nrf2/HO-1/NF-B signalling pathway, thereby diminishing the beneficial effects of AA on RA

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