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FMOs in the liver metabolize TMA into TMAO once it is taken into the bloodstream

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Biopharm Drug Dispos 24:357365 Jamali-Raeufy N, Kardgar S, Baluchnejadmojarad T, Roghani M, Goudarzi M (2019) Troxerutin exerts neuroprotection against lipopolysaccharide (LPS) induced oxidative stress and neuroinflammation through targeting SIRT1/SIRT3 signaling pathway