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Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition

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We hypothesize that this reflects REM sleep dysregulation induced by uremia

One of the pathophysiological mechanisms involved in acute tissue injury is the activation of the systemic inflammatory response due to the contact of blood with non-endothelial surfaces, leading to the release of various inflammatory and coagulation factors and, ultimately, to the activation of effector cells ( Next, we describe the process of neutrophil activation and its contribution to acute organ injury with a further understanding of the pathophysiological mechanisms of acute organ injury in ECMO

F., Liday, C