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In hepatic encephalopathy, elevated blood ammonia resulting from liver failure disrupts the BBB via the Nuclear Factor -Light-Chain-Enhancer of Activated B Cells (NF-B) pathway, impairs mitochondrial function in astrocytes, and perturbs neurotransmitter balance through potassium dysregulation [67]

Non-neurological features included congenital lactic acidosis, cardiomyopathy, hepatomegaly, kyphoscoliosis, optic atrophy, roving eye movements, strabismus, and distal renal tubular acidosis [55-58,60]

Animal studies also show that PFOS exposure leads to impaired epithelial barrier function.[ref][ref] This is a timely topic when coupled with the research showing that most face masks (surgical, some N95, KN95) contain PFAS and that the main route of exposure is via inhalation.[ref][ref][ref][ref] In a study of over 500 teenagers, girls with higher PFOS levels were more likely to have problems with asthma.[ref] Related article : PFOAs and PFAS: Genetic interactions Air pollution: Exposure to particulate air pollution and other organic aerosols, except ozone, slightly increases the risk of asthma

Quagliariello, V

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