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Pharmacokinetic studies in children have demonstrated higher clearance, a shorter half-life and lower recovery of factor VIII compared to adults [see Clinical Pharmacology (12.3)]

doi: 10.1016/j.intimp.2024.112929

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Impact of copper on health Copper deficiency Copper deficiency is associated with impaired immune function and reduced T-cell proliferation, which leads to decreased production of interleukin-2 (IL-2)