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In terms of antioxidant defense, it not only directly scavenges free radicals (Singh et al., 2011) but also activates the Nrf2/ARE axis (Ashrafizadeh et al., 2020), driving the expression of key enzymes such as glutathione S-transferase and catalase to systemically alleviate ROS accumulation

Plant Physiol 153:313 Rinalducci S, Pedersen JZ, Zolla L (2004) Formation of radicals from singlet oxygen produced during photoinhibition of isolated light-harvesting proteins of photosystem II

Trimetazidine attenuates cardiac dysfunction in endotoxemia and sepsis by promoting neutrophil migration

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If you experience sleep disruption, try shifting your injection timing to morning or early afternoon