catalase and acetyl glutathione Antioxidant enzymes. CAT: catalase; GPX: peroxidase; GR: Oxidative Stress and Inflammation in

The sustained opening of mPTP leads to loss of mitochondrial function, which ultimately triggers apoptosis or necrosis and exacerbates tissue damage

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Funding This work was supported by Liaoning Province Key R&D Program Guidance Project (2020JH2/10300044) and Shenyang Science and Technology Program Project (20-205-4-050)

Other recent studies have also used murine models to study the benefits of NAC, and showed similar decreases in DNA damage [13]