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More importantly, nano-PROTAC could degrade 74% of the AR splice variant AR-V7 protein, showing the potential ability to overcome drug resistance

A growing number of studies have broadly examined the link between inflammation and cancer, supporting its role in promoting tumor initiation, progression, and metastasis

*Correspondence: Isabelle Boileau [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Purine metabolism Metabolites from the PPP, such as ribose-5-phosphate, can be shunted into creation of purines and pyrimidines