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(b) Similar changes occur in gonadal white adipose tissue (gWAT) with WAT adipocytes nearest to the glands (G) being selectively preserved while the other adipocytes were depleted (c) Within the tail vertebrae vasodilation is noted within the bone marrow, however, the constitutive bone marrow adipocytes (cBMAT) remain filled with lipid

Electron leakage occurs when NAD and FAD become overly reduced or when quinone is partially reduced to semiquinone, increasing the likelihood of superoxide or hydrogen peroxide formation within mitochondria

Measuring climbing ability is utilised as a way of measuring healthspan, and both DR and reduced IIS can improve ageing related climbing ability 34,35