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IMDs leading to megaloblastic anemia through impaired folate metabolism are caused by enzyme deficits leading to DNA synthesis: Dihydrofolate reductase (DHFR) deficiency and formiminotransferase-cyclodeaminase deficiency

Journal of Ethnopharmacology 2009 124(2) 182-8

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A metal-sensitized sonocatalyst idea has been presented to tackle these issues, wherein noble metals augment the sonocatalytic efficacy of semiconductors