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Based on the December 2025 filing, that puts a decision around OctoberDecember 2026

This patient's isolated drop in weight with preserved length strongly points to an early nutritional deficit rather than an intrinsic systemic disease

Given that AGEs are primarily metabolized in the liver and excreted through the kidneys 45,46 , the decline in serum AGEs levels observed here may reflect hepatic metabolism and clearance rather than direct cutaneous effects

This multiscale delivery system, utilizing BMSC differentiation, holds potential for clinical applications in IVD regenerative therapy

doi: 10.1016/j.biopha.2023.114241 38 LvYWuMWangZWangJ