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Hoeg et al., 1986, J

For instance, an initiator that induces early DNA lesions may create pre-mutated cells that become highly susceptible to the proliferative or pro-inflammatory signals generated by a promoter [258]

Cancelas J, Gottschall J, Rugg N, Graminske S, Schott M, North A, et al

The anti-apoptotic effects of HRS may be mediated through both the upregulation of cytoprotective genes and proteins like Bcl-2 and the inhibition of apoptotic pathways involving caspases [12]

Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14: 1) is not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism