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Patients who have ever smoked showed a lower total and trabecular BMD, and lower trabecular parameters, but no difference in cortical parameters

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in the event of a deficiency of B12, B9, or both, cells are unable to successfully duplicate DNA and there is a delay in cell division, which leads to an alteration of this process, stalling in the growth phase and being unable to move on to the mitosis phase

They are a rich source of soluble factors such as ROS, peptides, cytokines and enzymes that exert antimicrobial activities [257]