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The role of precision nutrition in the modulation of microbial composition and function in people with inflammatory bowel disease

However, when mitochondrial quality control (MQC) mechanisms, particularly PINK1/Parkin-dependent mitophagy, are compromised, damaged mitochondria accumulate, mtROS and mtDNA leak into the cytosol, and Nrf2-driven defenses are overloaded [18]

Quantitative data obtained from flow cytometry analysis exhibited a consistent trend, as depicted in Fig

However, this technique has important limitations as shown in a study performed by Maclay et al