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Since the glucose-consuming phase exhibited sufficient nitrogenase activity to allow active glutamate production, we hypothesized that an increase in the initial glucose content of the medium may extend the glucose-consuming phase, thereby sustaining nitrogenase activity to produce more glutamate

To fulfill the objectives of the guideline, this revised edition has been published to incorporate these evolutions

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A landmark study published in Science Translational Medicine in 2015 provided molecular evidence for this association