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Age, sex, BMI, diabetes status, genetic markers, microbiome composition, and lifestyle factors all influence outcomes

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Multiplex analysis of urinary cytokine levels in rat model of cyclophosphamide-induced cystitis

The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)