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Muscle Recovery and Energy Production : The inclusion of Vitamin B15 helps combat fatigue by improving muscle oxygenation

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In one 2014 case study, a 64-year-old woman was on the hCG diet when blood clots developed in her leg and lungs

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If results are weak into the remodelling phase and starting dose was sub-3.2 mg, a dose increase and protocol modification may be warranted

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NEWS Correction 06 January 2026 Update 08 January 2026 2025 FDA approvals Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription 17.99 / 30 days cancel any time Subscribe to this journal Receive 12 print issues and online access 169.00 per year only 14.08 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout Nature Reviews Drug Discovery 25 , 81-87 (2026) doi: Updates & Corrections Correction 06 January 2026 : The brand names of Nuvaxovid and Mnexspike have been corrected in Table 2

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Sex Hormones and Cardiovascular Health The effects of hormone replacement therapy (HRT) on cardiovascular outcomes in menopausal women can vary depending on the type of hormone used (synthetic versus bioidentical) and the route of delivery (oral, transdermal)

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