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The reduction of ZIP14 in obese patients negatively correlated with both leptinemia and adipose tissue leptin levels in obesity, as in ZIP14 knockout mice, which exhibited higher levels of leptin

Though we have made great progress in understanding the pathogenic role of ferroptosis in PD, the precise role that ferroptosis plays in the brain damaged by SARS-CoV-2 and how it initiates the inflammation that ultimately causes brain damage is unclear

Unbiased sub-clustering of these cells revealed seven distinct cell types (Figs

5 Interactions between three metabolism-linked cell death pathways Ferroptosis, cuproptosis, and disulfidptosis are programmed cell death pathways triggered by metabolic stress

Nat Commun 8 (1), 1177 (2017)