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Recall from Equation 16.15 that the ionization constant for a weak acid is as follows: If [HA] = [A ], this reduces to K a = [H 3 O + ]

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For context, the underlying lyophilized peptide can remain stable for one to two years or longer when stored correctly before reconstitution, making the post-reconstitution window the most critical and time-limited phase of the entire storage cycle