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Thats because vitamin B12 is bound to protein and can only be released by digestive substances in the stomach (hydrochloric acid and gastric protease) to be absorbed

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However, for those with inactive disease it may be reasonable to stop at the start of the third trimester, in line with peak foetal development[1]

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These side effects often go away if you stop taking the drug temporarily (which should only be done under a doctors supervision)

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