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The side chains of residues Glu256, Phe90, Val238 and Phe264 show tightly hydrophobic contacts and/or - interactions with the T1 molecule

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Now, there are more potent anti-inflammatory drugs and biological agents, which may limit the application of AMDs in RA treatments ( 5.3 Modulators of STING Recent studies have delved into compounds that modulate STING activity and their potential utilization in the treatment of RA (54, 70)