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Effects of Saccharomyces boulardii Supplementation on Nutritional Status, Fecal Parameters, Microbiota, and Mycobiota in Breeding Adult Dogs

While important to know about, this warning is based on animal studies and the link has not been found in humans

(See BOXED WARNING and PRECAUTIONS.) The test dose should be administered in the buttock using the same technique as described in the last paragraph of this section

It depletes key nutrients the immune system depends on and it then creates a state of chronic inflammation that, over time, starts damaging tissues that the bacteria itself isn't even directly attacking