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Common Prior Authorization Criteria BMI documentation: Most states require a documented BMI of 30 or greater, or 27 or greater with at least one weight-related comorbidity (hypertension, type 2 diabetes, dyslipidemia, obstructive sleep apnea) Failed lifestyle modification: Typically 3 to 6 months of documented dietary counseling and physical activity recommendations that did not produce adequate weight loss Step therapy: Some states require patients to try and fail less expensive medications (phentermine, orlistat) before approving GLP-1 coverage Provider qualification: Some Medicaid plans require the prescriber to have completed training in obesity medicine

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Additional studies have confirmed its metabolic benefits including improved triglyceride levels and insulin sensitivity

Tesamorelin & CJC-1295 (Mod GRF 1-29) & Ipamorelin Studies on Liver and Metabolic Markers Tesamorelin has been investigated in relation to hepatic lipid accumulation and liver fibrosis progression

Hydroxocobalamin also binds nitric oxide, particularly in the absence of cyanide