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Description

Signs include persistent fatigue, paraesthesia (pins and needles) in hands and feet, difficulty with balance, memory problems, mood disturbances, and megaloblastic anaemia

Grade: USP / research grade

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Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R