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UAMC-3203 induced (around 20%) weight loss in HFHFD compared to vehicle, but not in SD, and attenuated gonadal adipose tissue mass

The expression of ERCC6 at both mRNA and protein levels is reduced in LECs of ARNCs, and is associated with methylation of a CpG site in the ERCC6 promoter, suggesting epigenetic regulation of ERCC6 in LECs of ARNCs (108)

Transcript-level expression analysis of RNA-seq experiments with HISAT, stringTie and ballgown

green: Ex/Em = 485/535 nm) was measured using a SPARK microplate reader (Tecan, Austria)

The FDA recently announced changes in the labeling of ezogabine to warn about the risks of retinal abnormalities, possible vision loss, and bluish skin discoloration, all of which could be permanent