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The concentration of Human APOE in the samples is then determined by comparing the OD of the samples to the standard curve

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doi: 10.1016/j.celrep.2016.12.011 315 SowellE

(2024) 9:e175479

Similarly, in high-fat dietinduced (HFD induced) pre-diabetic rats subjected to cardiac ischemiareperfusion injury, administration of the mitochondrial fusion promoter M1 (2 mg/kg), either alone or in combination with the Drp1 inhibitor Mdivi-1 (1.2 mg/kg), significantly reduced mitochondrial dynamics imbalance, ROS generation, swelling, and membrane depolarization, which collectively decreased infarct size and arrhythmias while improving left ventricular function [177]