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Knockdown of HSPA5 inhibits the migration and invasion of bladder cancer cells by inhibiting the vascular endothelial growth factor A (VEGFA)/vascular endothelial growth factor receptor 2 signaling pathway, and overexpression of VEGFA alleviates the effects of HSPA5 downregulation

Pharmacokinetic properties and drug interactions of apigenin, a natural flavone

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Instead, it can be mimicked by agents that induce the unfolded protein response (UPR), a signal transduction pathway activated by the accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER) [65]