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To fully understand all these concepts, the most important thing is to know what oxidative stress consists of: it is an imbalance between the production of reactive oxygen species (ROS) and the ability of a biological system to quickly decode the reagents that can cope with them (antioxidants) or to repair the resulting damage

Acknowledgements We thank Congfeng Xu for assistance with fluorescence-activated cell sorting analysis

Cell culture studies have demonstrated that IGF-1-enriched serum protects cerebellar neurons against OS induced by H 2 O 2 [45]

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At the immunological level, MPs disrupt homeostasis through several interlinked molecular pathways, precipitating inflammatory responses, oxidative stress, and apoptosis, ultimately leading to immune dysfunction and related diseases