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Shindel AW, Lin G, Ning H, Banie L, Huang YC, Liu G, et al

Although AOX therapy offers theoretical benefits, clinical outcomes remain inconsistent

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The rearrangement is accompanied by a cis-trans isomerization of this proline, which likely increases the energy required for the transition between the 2 states, and may play a role in the stabilization of the active conformation at the water/lipid interface