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10.1097/hco.0000000000000812 91

FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism

Conditions like CRPS, fibromyalgia, and neuropathic pain involve central sensitization, where the nervous system amplifies pain signals beyond the original injury

Otherwise, a disconnection would result in futile, cyclic synthesis and degradation of cellular components and biomass

Specifically, M1 macrophages predominantly utilize glycolysis to sustain their pro-inflammatory functions, whereas M2 macrophages depend on fatty acid oxidation (FAO) and oxidative phosphorylation (OXPHOS) [14]