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Proc Natl Acad Sci U S A 115(37):E8717e8726 Acknowledgements The figures of this paper were created by Biorender.com

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In addition, the ME green module (1130) presented a dramatically high negative correlation with TW ( r = 0.75, P- value = 4e-04) and TL ( r = 0.77, P- value = 2e-04), and the ME red module (831) showed a significant positive correlation with TW ( r = 0.8, P- value = 6e-05) and TL ( r = 0.75, P- value = 3e-04)