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51 Diseases related to copper dysregulation Given that either Cu deficiency or accumulation exhibit adverse health effect, it is important to note that the inability to maintain Cu balance has been associated with a wide range of pathologic conditions, including MD, WD, neurodegenerative diseases, cancer, and cardiovascular disease

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Its effect is clearest in ADHD and minimal in healthy people, and because it tunes signaling rather than changing tissue, it stays a nootropic

After 24 h medium was discarded as recommended in [9] and 110 l medium without CuCl 2 or CuSO 4 containing 10 l CCK-8 Solution was added