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We further discussed the cellular and molecular mechanisms of arachidonic acid pathwaymediated regulation of cardiometabolic diseases and highlighted the emerging clinical advances to improve these pathological conditions by targeting arachidonic acid metabolites and pathway factors

13,168 Diagnosis involves a comprehensive clinical evaluation, including detailed neurological examination, electrophysiological studies like NCS and electromyography (EMG) to assess motor and sensory fiber function and localize lesions, as well as imaging studies such as magnetic resonance imaging (MRI) to exclude compressive or structural causes

Finally, the ongoing challenges for the clinical translation of NPPC-based therapies are discussed, along with potential directions for future research

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